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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba7146ce2186c1d89fdd37631bf8bc2a074def8ee11751ba1e798f432c9be1fe' 
  AND token = 'CtkTQF4iNSZoCHdM1tnP2uf+v1QduL4jVHiCAS8NqR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}