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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d01f4b1e0575567176807c61785b47d72e8c75cf9a39f655ba7d0999247b055' 
  AND token = 'Va9054aEXgJJL3RT2I+h0xIiIhIb4CJenh5StaFMu+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}