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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201322da858dc004f42d6485ccb66d928569226f120bf6b971f0ae5e24721e78' 
  AND token = 'sBrddt+Ky35s7EwhephbYyKWd10Zz6PR8x8ux6WBsV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}