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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6d7643cd6090291273fea4a42335e51a4556826cb2e4d6a9edf44b1327aa33' 
  AND token = '6PNkQh8Y06qexuZJ3xAdTCT8bmHR5rpwIwpLB5hNGAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}