SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a84c24765d07f0273474edc93feeda5dee5031b272d81f447217be4ff4d34e' 
  AND token = 'SIo1MdL/E9ASAzhOGuyC+wX1HYuByPWbuV0Gbsy1QMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}