SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18df760fd9b41b340e465e6f4af50b4e989e1e1acb26e60cc37c5ee8dbaef32' 
  AND token = 'q6D79/NRI2HXwIYPdo5/61F1r3V4DRfT3lUg+eyXSm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}