SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffc4657df7b098b96f7363f2108ab702ff8fca5063b781fd6114e9f089461282' 
  AND token = '09IMncoNNGOxQYKnzSE7s7/4WIXYwCvO3NDK1kjN4vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}