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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4e15f4cb69a29a12a6163f2affc0aec3db96c1d4469a98abca5fbb95285188' 
  AND token = 'yz3ce+4FehJpyo9yuWDgmnb46Fc/69Q/jWk5UU1/ylY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}