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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761c95e9ca9a3b071421b518264faee9d12281e7febffe30538853565054f577' 
  AND token = '1Q7zUHT22s1bUWQtOOI/AEyFyaaXg+jhNheDW1xzYWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}