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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc7383186e088285873e85e8a69d6f32024c4ab4a041ce77dbdd354e6dda584e' 
  AND token = 'RIKTSSj6IDojTTOHsGxRaDq/v7KeuKYDM6QLDHBPVgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}