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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4493afae8457efd326a1a61d1a0ebc78a6d5f40263f9b4beaf29d936675165dd' 
  AND token = 'Ug6redHUZ2X5P57Xcj+6P8ELA0tctctxlJcy0sy19Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}