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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac88303c3219c30af0747b29e31a000859a3c409ecc5bec93277b005b9b6d14' 
  AND token = 'G6cbhtXQdynNbm9w//U80389WbTk/oCw1jhQmb2ms3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}