SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82170c46e0c4b2d8affe621af4e1fc4fa2920cc0523cf6ee9d4f2d1a1bc7112c' 
  AND token = '7rS1iRNPYDTkbWUYXg/xo+ChcfT0iTbLBMsmh4N/kuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}