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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816471f2e4437551e7578a8f3019e4dc6382dd42bbbbc2e10dfec6550b50919b' 
  AND token = 'GenAt85GrSZ4xHM6XbCl/qxhs0RI3DHjHJAJbPwqXLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}