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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b6e6aae4c29ba0ab1baef216bb765b88ef1d1fe8cb135c077277fed2036b7d' 
  AND token = 'HBBHmyMSd+0Q0SBKXDzYftuZNWrM8AhzK4iyIUUlJ+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}