SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eabf49f0549b13d1f687a760e130f01c6134e590d13dec5d349520870fa4d2c0' 
  AND token = 'VJpQxcBKuv4Mr6WxTShSRKKsd39EKr074ilyL1fXnBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}