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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3d662d76f64d81f995be4a2c85e47a351b9800f6b57780f9bc4f291746c8a8f' 
  AND token = 'lMaIYpYbYx5Mg1X0qhcmZlhpx3N0bIdZmpk7Lc6eFSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}