SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78ce9adb839d78f636e7df47130b34084f64ac6599c93b36f93d5268bbad990' 
  AND token = 'AXMFR8Nt2cGsteT2yl8M45pQd6QvtcbMdd4lvSVj1AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}