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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436c0c88ce8b259e680abf0e31d3822bb953a1a560eedb68e3c9fb9592fb1bca' 
  AND token = 'EKetkkbaIjCiXZIKDF9WOTblTBVLSNGJcLrOzqVhbUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}