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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28ddcb2221ae486efbad4230942c410f13b2e35991f30821e480542d9ee2cbdf' 
  AND token = '2a+exG8neyyHoYvxK7aSqlTN1OJvsXzzp4x4ukRd9HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}