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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad0e43dd9f2729832d4cc32f228ede5d4d4233ab516ae310c9a089a4fcf819b' 
  AND token = 'DeZlGvuxIYh9WuAwx+dhcwz2lCuZ7HAGyHTmWjxPO0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}