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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8a04470f6af1e4ce0f2ecb2ebb25feffaaeb0a1e501e9b385f9f6b968d24ac' 
  AND token = 'npY4qjGxI01u/kFfcTSBFEcD9HtBehsbwR7qFuR/ycE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}