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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1271eceb16b8b219d27f5d43d0902c33646bf369d3229849b69f69044df8d4de' 
  AND token = 'R0L3N2fr4uWCcZYW9Soa5jWozt4poNF5QKZhakQNQaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}