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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48198f56a6d429de60520993f2355f01513e5917b02470aaa2aaa2670ed164e0' 
  AND token = 'ctxIo3dGCha3Bu5Q2banKytW1OTgHEMSAvM4ZyMD1pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}