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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8544995b5365308e8dd3b045f9632d44a769adbd37bdeb7fe385e434049c381c' 
  AND token = '/amXU9F9/yfCrosBK2uEIqe/u//6dDpsaQP6UJ3IRNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}