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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322d2767930a76dc196e5b6255dd5532cd1d149ddcabc92bd57316cea711c231' 
  AND token = '80/w35trxPyePP48mSy/+YXueL36zCdsCv5nxEUWt28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}