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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53abf0005f4135f74ee007e0d2516258fccc563ec48069b69e4a91e66148a27' 
  AND token = 'dAT+PptvB3269g+YwcINFZhlMM0/WEMa8sjB5u5zFOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}