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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4181e755784fa111d8c4579d5d6e5c1c82e8389e7f6b581727301e24316a9ae5' 
  AND token = 'MtkLlJoTmsmZ51vrBAcbZxWALbNoGrTBGcwb1Pl2m6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}