SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '804bc53663e94885862d304c34e838e75a4ce7dd15c410c04f91e2d15f787f9f' 
  AND token = 'FMk++QkADS4KeF41Trl80cDoxJRjU92thxj7aww4sI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}