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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a799ce3e2a1202f7960883f4c0fa444be12e26fe5077a9163aaf92daf7185c' 
  AND token = 'naRY2f+owLzCZ3JcOYH7XQs2yo1yzooqNTLCYFRyQL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}