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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005f2f91ef7afa729ef62e7ad1d804464437d1e4330d037493069a3414ef14d8' 
  AND token = 'CnPG/uB5cGtAL19M+kf3B6v+qd3aoH20Ys9jzQ2xuts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}