SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ce3d81ff6a486f1cb6fee63def998326a54bfe83224bfca60e9d0df7e476e4' 
  AND token = 'w1v9LKuA6zVF/wzI7lH29a3xpmI50boxa1f3rWlMpXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}