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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1065f371a25746fa53c3f4cbb6d9257b68da6c88e45dcca85ac06993ecb1f55' 
  AND token = 'nlrjm0RhwAc1M6ahMJWp0mphrBW1Ov2EV68rM08Wcb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}