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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b61c1d3c53cca21b07b87fc723767531c7f157dd81e69e19e636e9d4920cb241' 
  AND token = 'qT5zeRXGu05uNHgbYDFc41w2es5hOSg0mZhaQZGxkDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}