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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fbd0e4f3ccd8e37862330b9da28d43aa75f7869840cd488a77477d4e07aa0df' 
  AND token = 'x64LvSEO/vzJRvYgu+H2Ewc+7zuMNlhRsZyKU7wP6S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}