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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e848a85a45d8aaff2a22de0b6f0a4c1660ccf7eb14bda242d034177d143d909e' 
  AND token = 'gIReZ1GA560djxb4TPj+PWbUoD/8hZLepCl7hrBM71M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}