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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4114a2b3afea6ab60db9a0df2365669dd1deb3bf0c55a1c255f28bf65bb6754' 
  AND token = 'wMFppOtkUtSuPzCA0+PsLXN1Il7lCzy4qG8vkBGbtKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}