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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b3dcb8102f8659fcf195529eea5ae42b6d71738ad5ace6fc482397931c38d6' 
  AND token = 'KiW9HiWaDm5gnGiqlxdaE+iXXG/jHRUPnA2iL9abwZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}