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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c116e7b1439358be722f9bbfc1da98552e9ce19f68ce2706f253518c3f246270' 
  AND token = '6Vp18MnixeF9nbRfgGumtixIY5btxqtBnY3sgVEV1vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}