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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad01f6982470451df435f4ba972da9e353c4d34563b3130e21fd9a01936fe8bd' 
  AND token = 'yB2w6Oji2X7l1j1Nr9qUaEIxtXDzkgBZXuBxiD0XOSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}