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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9bc18abdcaf440d3dad504952eca985a6c47b1c88131091f1ce1c627458dc4' 
  AND token = 'V0EfSUqKKTPy7O4h7ESS+LHZ+B4ptWSDoHFEVf61uwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}