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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ed81ba737b7bcfa15cb42a10982b341fdbea2cf34392200744823c9322165f' 
  AND token = '3ndwZF7+Gk1TjHk3fGaXXk28FkgE5+PftD7jC/wLhbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}