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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7ac3937423dc315ea0f339585fee36179d2b75051e7302f4b7b3615787a135' 
  AND token = 'OAi+9ap4VLi0aMOcnCdN92iD9i1oxqUedWWP0VAN9wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}