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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291b2d7c684e761f741611edc767b3e44e98cbbdcf2157d5e8505c8eba97e9e4' 
  AND token = 'UbCkoT+5wDeQHQSkivdtDVDuHxiSKXOfBjVLsrNTVtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}