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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a225f2c2f2eba4a374b44cc39743adca412eeb79a7eae00b1df9156f84164f4f' 
  AND token = 'R0XIXDB6pA9x37GtHTc6X4ttDT9NJ30rh0dwkg+t8gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}