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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7294ca219ca4b158cbf4adccfa369d7335519c59853e15e046dbb7d695c32771' 
  AND token = 'Cr2KGjeiHFdb6gbfPMOq8KuZB5vd81dgCX2XHN0Gnh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}