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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6430a375c485d3e9997e6b1133f94631d9d61bdcc5f76e469d994d176d028736' 
  AND token = 'oAmI3zdy+p8ko3u3/UarmZ86Kb7ThAkNlk6baODd8NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}