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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5941cb652c17260cd784e71b6e807d937e43f32db3d1842e2985357d83792a' 
  AND token = 'E0NNuzNCuycfD+IawSTwEWmPqM8lwvfmZ9aF3GHBtL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}