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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4653978b0b8a6c46cec7fe931420942f18f90b279d374772d1caf455193ad6' 
  AND token = 'r/p18qn44ATMnbLpjqjCdp0CNsUdE5k0yHN0rPkwwow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}