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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c68df6138931e2505b38df7d1d6c54b2cc15f6a77e83aeebfb6dab01da2f785' 
  AND token = 'K6ma4MzVZkTII+x4xfg0aaI6XMi57uvk7CpMAlkJIUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}